Pregnancy in premature ovarian failure after therapy using Chinese
herbal medicine
Chao SL, Huang LW, Yen HR.
Department of Gynecology and Pediatrics, Center for Traditional Chinese
Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan.
We present ovulation that occurred after the administration of traditional Chinese
herbal medicine for 3 months in a woman with premature ovarian failure (POF)
and secondary amenorrhea for 8 years. Traditional Chinese medicine concentrated
herbal extracts of cooked rehmannia, Chinese yam, wolfberry fruit, dogwood
fruit, cyathula root, dodder seed, antler glue, tortoise-plastron glue, epimedium
and morinda root were prescribed, which were a modification of the herbal
formula Zuo-gui-wan. When the patient discontinued the Chinese herbal medicine
treatment and tried therapy with clomiphene citrate, neither ovulation nor
conception occurred. Eight months after beginning clomiphene citrate therapy, the
concentrations of follicle stimulating hormone and luteinizing hormone were still
in the postmenopausal range. The modified formula of Zuo-gui-wan was
prescribed again and the patient conceived 1 month after taking Zuo-gui-wan.
Thus, we suggested that Chinese herbal medicine restored ovarian function
effectively and promptly, and offers another option for treating infertility in
patients with POF.
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